(= Shp-1, Shp-2)
Protein tyrosine phosphatases with SH2 domains. Are recruited to ITIM motif of receptor tyrosine kinases and play an important role in the control of cytokine signalling. Shp-1 is important in regulating antigen responses in T-cells and the mouse mutant ( motheaten ) is immunosuppressed. Shp-2 is more ubiquitously expressed and functions downstream of a variety of growth factor receptors and has a role in cell spreading and migration; the homozygous mouse knockout is embryonic lethal.

Dictionary of molecular biology. 2004.

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  • SHP — steht für: Samoczynne hamowanie pociągu („Selbstständiges Bremsen des Zuges“), ein polnisches Zugsicherungssystem; siehe SHP (Zugsicherung) Shaft Horse Power, englisch für „Wellenpferdestärke“, eine der Pferdestärke verwandte Maßeinheit Shapefile …   Deutsch Wikipedia

  • SHP — or shp may refer to: * Saint Helena pound, the currency of the British overseas territories of Saint Helena and Ascension Island * Seton Hall Preparatory School, a school in West Orange, New Jersey * Shaft horsepower, the power delivered to the… …   Wikipedia

  • shp — abbrev. shaft horsepower …   English World dictionary

  • SHP — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom.   Sigles d’une seule lettre   Sigles de deux lettres > Sigles de trois lettres   Sigles de quatre lettres …   Wikipédia en Français

  • shp — See shaft horsepower. Also, SHP, S.H.P., s.hp., s.h.p. * * * …   Universalium

  • SHP — abbreviation Usage: often not capitalized shaft horsepower * * * See shaft horsepower. Also, SHP, S.H.P., s.hp., s.h.p …   Useful english dictionary

  • SHP (Zugsicherung) — SHP Gleismagnet SHP Fahrzeug Lesespule Das Zugsicherungssystem SHP (Samoczynne …   Deutsch Wikipedia

  • SHP (Saint Helena Pound) — The currency abbreviation for the Saint Helena pound (SHP), the currency for Saint Helena and Ascension Island. The Saint Helena pound is made up of 100 pence and is often presented with the symbol £. Saint Helena and Ascension Island are… …   Investment dictionary

  • shp — abbreviation shaft horsepower …   New Collegiate Dictionary

  • SHP — In currencies, this is the abbreviation for the St. Helana Pound. The currency market, also known as the Foreign Exchange market, is the largest financial market in the world, with a daily average volume of over US $1 trillion …   Investment dictionary

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